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Under the name of T-cell lymphoma, or PTCL, hide 12 different subtypes. T-cell lymphomas are rare for every person diagnosed with T-cell lymphoma, there are 10 diagnosed with B-cell lymphoma. The first is to provide education about these rare cancers to patients and family members by means of hosting educational forums and providing online literature. Therefore, it is important that patients check with their physician or with the Lymphoma Research Foundation (LRF) for any treatment updates that may have recently emerged. Treatment strategies, which are limited and require tailoring based upon likely underlying etiology, include growth factors, thrombopoietin-receptor agonist, stem cell boost, transfusion support, and abrogation of infection risk. T-cell lymphomas are a family of aggressive (fast growing) lymph node cancers that originate from an immune T-cell. What is the T-Cell Leukemia Lymphoma Foundation The T-Cell Leukemia Lymphoma Foundation is a non-profit organization that was formed in an effort to fulfill several purposes. Treatment options may change as new treatments are discovered and current treatments are improved. Commonly cytopenias resolve over time and evidence for effective interventions is often anecdotal. Bone marrow biopsy in patients with prolonged or late cytopenias is important to evaluate for primary disease and secondary marrow neoplasm in both pediatric and adult patients. Early and prolonged cytopenias often correlate with severity of cytokine release syndrome or immune effector cell-associated neurotoxicity syndrome.

Early cytopenias are typically attributed to lymphodepletion chemotherapy however infections and hyperinflammatory response such as immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome may occur. These cytopenias may cause additional sequelae, decreased quality of life, and increased resource utilization. Variable etiologies of these cytopenias, some of which remain incompletely understood, create clinical conundrums and uncertainties about optimal management strategies. Cytopenias occurring after CAR-T infusion invariably manifest early (90 days). Increasing use of chimeric antigen receptor T-cell therapy (CAR-T) has unveiled diverse toxicities warranting specific recognition and management.